1. per se
1. He will likely be charged with the per se offense of driving while intoxicated, or an equivalent per se offense. 2. The mere threat of action does not per se constitute duress (=unlawful pressure).
He is not programmer per se.
2. by itself
Englisch Wort "samo z siebie"(by itself) tritt in Sätzen auf:
Unit 1 | Introductory Chapter |3. of its own record
4. in and of itself
Yes, in and of itself, your statement isn't a problem. But you have to understand how it sounded in the context of the conversation. 2. The idea in and of itself is not bad, but the side issues introduce many difficulties.